We use our own and third-party cookies to optimize your experience on this site, including to maintain user sessions. Without these cookies our site will not function well. If you continue browsing our site we take that to mean that you understand and accept how we use the cookies. If you wish to decline our cookies we will redirect you to Google.
Already have an account? Sign in.

 Remember Me | Forgot Your Password?

Vitamin Supplement Helps Defend Against Inflammatory Bowel Disorder

January 22, 2010: 07:46 AM EST
A vitamin widely found in supplements or cod liver oil, can counter the effects of the inflammatory bowel disorder Crohn's disease, Canadian scientists report. Vitamin D directly affects the Beta defensin 2 gene, which encodes an antimicrobial peptide, the NOD2 gene that alerts cells to the presence of invading microbes. Both Beta-defensin and NOD2 have been linked to Crohn's disease. If NOD2 is deficient or defective – for example, in sunlight-deprived people from northern countries – it cannot fight intestinal tract invaders. The researchers say their discovery “shows how an over-the-counter supplement … could help people defend themselves against Crohn's disease.”
Tian-Tian Wang, Basel Dabbas, et al., "Direct and indirect induction by 1,25-dihydroxyvitamin D3 of theNOD2/CARD15-beta defensin 2 innate immune pathway defective in Crohn's disease ", The Journal of Biological Chemistry, January 22, 2010, © American Society for Biochemistry and Molecular Biology
Vitality & Better Living
North America
Research, Studies, Advice
Developed by Yuri Ingultsov Software Lab.