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Vitamin E Supplementation Improves Livers Of Some With Fatty Liver Disease

April 28, 2010: 10:15 PM EST
There is no approved medication in the U.S. for fatty liver disease, also known as nonalcoholic steatohepatitis (NASH), a growing health problem characterized by excessive fat in the liver that leads to inflammation and liver damage. But a new study found that a daily regimen of vitamin E supplementation improved the livers of a significant number of patients and may offer some hope as a potential treatment. In the placebo-controlled 96-week test, half of the NASH patients ingested 800 IU daily of a natural form of vitamin E. About 43 percent showed significant liver improvement, scientists reported, while only 19 percent of those who received a placebo improved. Scientists stressed that the treatment did not help all patients, and that diabetic patients were not included in the study.
Arun J. Sanyal, M.D., Naga Chalasani, M.B., B.S., et al., "Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis", New England Journal of Medicine (advance online edition), April 28, 2010, © Massachusetts Medical Society
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