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Vitamin D Supplementation May Help Improve Control Of Asthma

September 1, 2010: 07:34 AM EST

A U.S. study has found that prescribed asthma medications supplemented with vitamin D may reduce inflammation and aid in asthma control. Researchers noted that a vitamin D deficiency is associated with “increased airway hyper-responsiveness, lower pulmonary functions, worse asthma control, and possibly steroid resistance.” After analyzing six decades of literature on asthma and vitamin D, the researchers concluded that vitamin D supplementation could help improve asthma control by preventing the influx of inflammatory cytokines in the lung and increasing the secretion of interleukin 10 by T-regulatory cells and dendritic cells. They cautioned that vitamin D should not replace an asthma medication, but only supplement it.

Manbir S. Sandhu, MD, Thomas B. Casale, MD, "The role of vitamin D in asthma", The Annals of Allergy, Asthma & Immunology, September 01, 2010, © Elsevier Inc
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