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Researchers Discover Why Resveratrol From Grapes Shows Anti-Obesity Effects

January 7, 2011: 10:51 AM EST

The natural polyphenol resveratrol found in grapes and red wine has been shown in numerous studies to offer significant health benefits, and a new study shows why. Researchers in China and the U.S. have discovered that resveratrol stimulates the expression of adiponectin, a hormone derived from cells that manufacture and store fat. The hormone itself has numerous beneficial effects on obesity-related medical complications, and together with resveratrol, displays anti-obesity, anti-insulin resistance and anti-aging properties. “Results from these studies should be of interest to those who are obese, diabetic and growing older,” one researcher said. “The findings should also provide important information on the development of novel therapeutic drugs for the treatment of these diseases.”

Anping Wang, et al., "Up-regulation of Adiponectin by Resveratrol", The Journal of Biological Chemistry, January 07, 2011, © American Society for Biochemistry and Molecular Biology
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