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Probiotics Might Provide Novel Treatment For Inflammatory Bowel Disease

January 19, 2010: 09:53 AM EST
Probiotic microbes that produce butyric acid that reduces inflammation and strengthens immunity in the intestine could be used to treat inflammatory bowel disease (IBD), Belgian and British researchers have found. An inflammation of the gastro-intestinal tract that causes severe diarrhea and abdominal pain, IBD affects 20 out of 100,000 genetically susceptible people in Europe and North America. Crohn's disease and ulcerative colitis are the most common manifestations of IBD, which results from an overactive immune response linked to an imbalance of “good bacteria” in the gut. In addition to its anti-inflammatory effects, butyric acid strengthens intestinal wall cells.
Filip Van Immerseel, Richard Ducatelle, et al., "Butyric acid-producing anaerobic bacteria as a novel probiotic treatment approach for inflammatory bowel disease", Journal of Medical Microbiology, January 19, 2010, © Society for General Microbiology
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