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Maturing Fat Cells Become Less Insulin-Sensitive In Presence Of Fructose

June 20, 2010: 10:15 AM EST
High levels of fructose present as a growing child’s fat cells mature may lead to an increase in abdominal obesity, a condition associated with increased cardiometabolic risk, according to a new British study. Fructose apparently makes childhood fat cells mature into belly fat cells that are less able to respond to insulin. Abdominal obesity raises the risk of heart disease and Type 2 diabetes. Fructose is the sugar widely used as high-fructose corn syrup in soft drinks and processed foods and is frequently blamed for the widespread rise in obesity. The researchers studied both subcutaneous and visceral fat from 32 healthy-weight children who had not yet gone through puberty.
Georgina Coade, et al., "Fructose Sugar Makes Maturing Human Fat Cells Fatter, Less Insulin-Sensitive", Presentation, the Endocrine Society annual meeting, June 20, 2010, © The Endocrine Society
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