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Grafts Enriched With Stem Cells From Fat Show Promise In Cosmetic Surgery

January 25, 2010: 08:30 AM EST
The use of fat grafts enriched with stem- and regenerative cells showed a doubling in retention of the cell-enriched grafts in mice, indicating potential applications in cosmetic surgery. According to the researchers, the results reinforce earlier scientific observations, as well as data from a clinical study, and support the possibility that stem cell-enriched fat grafts could someday be used successfully in cosmetic and reconstructive surgery. Graft retention was improved because the fat-derived stem cells promoted cell survival and rapid angiogenesis (growth of new blood vessels) in the graft through growth factor expression that also prevents cell death.
Zhu, Min MD, MS, Zhou, Zhengyu BS, et al., "Supplementation of Fat Grafts with Adipose-Derived Regenerative Cells (ADRCs) Improves Long-Term Graft Retention ", Annals of Plastic Surgery, January 25, 2010, © Lippincott Williams & Wilkins
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