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Diet Containing Less Methionine Slows, Reduces Damage, From Alzheimer’s

June 2, 2010: 01:32 PM EST
A lifestyle change that includes a healthy diet with less of the amino acid methionine could not only slow or stop the progression of early-stage Alzheimer’s disease but also reverse some of the impairments that occur in the brain, U.S. scientists have found. Mice bred to show Alzheimer’s symptoms were fed either a normal diet or one rich in methionine, which has been associated with an increased risk of Alzheimer’s. Methionine is found in red meats, fish, eggs, garlic, and other foods. After five months, the group fed the methionine diet was divided in half, with one cluster continuing to eat high levels of methionine, while the other switched to a healthier diet. Cognitive impairment was reversed and brain plaques were reduced in the mice who ate the healthier diet.
Jia-Min Zhuo and Domenico Praticò, "Normalization of hyperhomocysteinemia improves cognitive deficits and ameliorates brain amyloidosis of a transgenic mouse model of Alzheimer’s disease", Journal of the Federation of American Societies for Experimental Biology, June 02, 2010, © Federation of American Societies for Experimental Biology
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