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Compounds From Digested Green Tea Effectively Inhibit Toxins Associated With Alzheimer’s

December 22, 2010: 09:11 AM EST

Drinking green tea regularly may help protect the brain from the harmful biochemical changes that lead to Alzheimer's and other forms of dementia and may also play a role in protecting against cancer, research by U.K. scientists has found. The researchers wondered whether the beneficial compounds (polyphenols) of freshly-brewed green tea survived the digestive process and were “bioavailable.” They found that when intestinal enzymes digested green tea, the resulting chemicals were even more effective against key triggers of Alzheimer's – hydrogen peroxide and a protein known as beta-amyloid – than undigested tea. Tumor cell models exposed in the lab to varying concentrations of the different toxins were protected by the digested green tea compounds. The next step is to find whether the same result is observed in human tests.

E.J. Okelloa, et al., "In vitro protective effects of colon-available extract of Camellia sinensis (tea) against hydrogen peroxide and beta-amyloid (Aβ(1–42)) induced cytotoxicity in differentiated PC12 cells", Phytomedicine, December 22, 2010, © Elsevier B.V.
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