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Company’s Mushroom Variety Suppresses Alzheimer’s Disease in Fruit Fly Study

September 28, 2010: 10:18 AM EST

A U.S. study in transgenic fruit flies has found that an enhanced  mushroom variety under study by Total Nutraceutical Solutions, Inc. can suppress and prevent Alzheimer's disease (AD). The genetically modified fruit fly over-expresses and over-produces the toxic neurodegenerative protein amyloid within its brain tissues. Amyloids are fibrous aggregates that have been implicated in Alzheimer's disease. The study found that a specific mushroom, Agaricus blazei Murrill (AbM), enhanced with natural organic vitamin D2, “dramatically suppressed and prevented Alzheimer's disease,” the company said. Synthetic vitamin D2 marginally improved survival of the AD flies, while synthetic Vitamin D3 worsened survival. The company, which is seeking a patent for the mushroom, said the findings show for the first time that a natural organic food can suppress and prevent a neurodegenerative disorder.

"Mushroom With Enhanced Vitamin D2 Naturally Suppresses Alzheimer's Disease in a Clinical Model", News release, Total Nutraceutical Solutions, September 28, 2010, © Globe Newswire
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