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Chemical Relative Of THC Selectively Enhances Sweet Taste

December 21, 2009: 08:23 AM EST
Endocannabinoids, substances produced in the brain and body that are similar to the active ingredient in marijuana (THC), selectively enhance sweet taste by acting on tongue taste cells, according to new research. Scientists administered endocannabinoids in mice to determine various physiological responses to sweet taste stimuli. In every case, sweet taste responses were enhanced. The effect was specific for sweet taste, however: endocannibinoids did not affect responses to sour, salty, bitter or umami (savoriness) taste stimuli. The researchers say the findings may lead to creation of new therapeutics to combat metabolic diseases such as obesity and diabetes.
Ryusuke Yoshidaa, Tadahiro Ohkuria, et al., "Endocannabinoids selectively enhance sweet taste", Proceedings of the National Academy of Sciences, December 21, 2009, © National Academy of Sciences
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