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Broccoli Extract Eases Symptoms Of Ulcerative Colitis In Mouse Study

July 1, 2010: 02:08 PM EST
An extract made from a food plant in the Brassica family, which includes cabbage, cauliflower, watercress and broccoli, has proven effective in easing symptoms of ulcerative colitis, an inflammatory bowel condition, in mice. The compound, called Phenethylisothiocyanate, or PEITC, apparently down-regulates many of the genes known to be up-regulated in human patients with colitis. In other words, PEITC acts on cells to decrease the quantity of cellular components like certain proteins produced abundantly in colitis patients. One of these proteins is a novel transcription factor that can read and interpret the genetic “blueprint” in DNA. PEITC reduces the damage to colon tissues. It also eases diarrhea and blood in stool alleviates weight loss. The researchers cautioned that the mouse results may not translate to humans.
Moul Dey, "Plant Extract May be Effective Against Inflammatory Bowel Disease", Ongoing study, South Dakota State University, July 01, 2010, © South Dakota State University
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