Antioxidant Supplements Do Not Prevent Hypertension In Diabetic Mothers-To-Be

June 26, 2010: 12:26 AM EST

British scientists who tested pregnant women 16 years and older with type 1 diabetes found that taking vitamin C and E supplements does not cut the chances of developing gestational hypertension, known as pre-eclampsia, and early delivery. Earlier studies had found that antioxidant supplements did not cut the risk of pre-eclampsia, but it was not known whether antioxidant supplementation helped pregnant women with diabetes. The researchers assigned women randomly to receive 1000 mg of vitamin C and 400 IU vitamin E (a-tocopherol) or a placebo every day until their babies were born. The rates of pre-eclampsia were no different between the antioxidant group and the placebo group. However, the researchers said, it’s still possible that vitamin supplementation might help women with a low antioxidant status.

Prof David R McCance FRCP, Valerie A Holmes PhD, Michael JA Maresh FRCOG, Christopher C Patterson PhD , James D Walker MD , Donald WM Pearson FRCPE , Prof Ian S Young FRCPath, " Vitamins C and E for prevention of pre-eclampsia in women with type 1 diabetes (DAPIT): a randomised placebo-controlled trial", The Lancet, June 26, 2010, © Elsevier, Inc.

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