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Antioxidant-Rich Diet Decreases Insulin Resistance In Obese People

June 21, 2010: 12:03 PM EST
Researchers in Italy reported that a diet containing high levels of natural antioxidants improved insulin sensitivity in insulin-resistant obese, but not yet diabetic, adults and enhanced the effect of the insulin-sensitizing drug metformin. Many studies have found that antioxidants such as vitamin E, vitamin C, selenium and carotenoids can forestall oxidative damage in cells. But this study is the first to show how natural antioxidants improve hormonal activity in obese people with metabolic syndrome, a group of risk factors for developing heart disease, diabetes and stroke. The authors noted that their four study groups experienced similar weight loss eating a Mediterranean style diet of fruits, vegetables, whole grains, etc. But the two groups who consumed the most antioxidant-rich foods had a significant decrease in insulin resistance.
Antonio Mancini, MD, et al., "Oxidative stress and metabolic syndrome: Effects of natural dietary antioxidants in obese patients with insulin resistance", Presentation, Endocrine Society annual meeting (Abstract P3-428), June 21, 2010, © Antonio Mancini, MD, et al.
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