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April 1, 2010: 11:28 PM EST
Scientists in the Netherlands applying the principles of nutrigenomics have found that a carefully compiled dietary cocktail of anti-inflammatory compounds had a positive impact on inflammation, oxidation, and metabolism, and could prevent diseases associated with being overweight or obese. In a placebo-controlled five-week clinical trial , scientists at a Dutch research organization gave 36 overweight men daily doses of substances known to have some anti-inflammatory effect: resveratrol, green tea extract, vitamin E, vitamin C, fish oil and tomato extract. According to the study, which analyzed gene expression, proteins, and metabolites, the additives reduced the inflammation of fatty tissue, improved vascular wall function and increased degradation of fats in the liver, indicating that a nutrigenomics approach could be effective in thwarting obesity-related disorders and diseases.
Gertruud CM Bakker, Marjan J van Erk, Linette Pellis, Suzan Wopereis, Carina M Rubingh, Nicole HP Cnubben, Teake Kooistra, Ben van Ommen and Henk FJ Hendriks , "An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach", Journal of the American Dietetic Association, April 01, 2010, © The American Society for Nutrition
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